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RegisterFactors Affecting Tmax [PK / PD]
Dear John,
Drug belongs to BCS class I that means it has good solubility and extent of absorption is comparable to IV.
Tmax is indicator of rate of absorption so drug might be getting completely absorbed but rate can be slow that means long absorption half life.
You can check Papp value and Maximum Absorbable Dose of that drug which might clear your doubt.
There are no of BCS class I drugs having long Tmax such as mematanine.
I hope it clears ur doubt.
Regards
Chiku
Drug belongs to BCS class I that means it has good solubility and extent of absorption is comparable to IV.
Tmax is indicator of rate of absorption so drug might be getting completely absorbed but rate can be slow that means long absorption half life.
You can check Papp value and Maximum Absorbable Dose of that drug which might clear your doubt.
There are no of BCS class I drugs having long Tmax such as mematanine.
I hope it clears ur doubt.
Regards
Chiku
Complete thread:
- Factors Affecting Tmax jag009 2012-05-03 23:00 [PK / PD]
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- Memantine! Chiku 2012-08-03 13:06
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- Memantine? Helmut 2012-08-01 15:09
- Factors Affecting Tmax luvblooms 2012-05-04 06:04
Ing. Helmut Schütz