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RegisterTTT method [NCA / SHAM]
Dear Hiren,
Please avoid SMS spelling in your messages on this forum.
Let me replace multicompartmental with multiphasic, then ?
Why make such a postulate ? Look at the PK profiles first.
1. F*** R2
2. I don't assume instantaneous distribution or monophasic elimination without looking at the PK profiles for each subject.
(Also look at Helmut's first message in this same thread).
Regards
Ohlbe
❝ And if u are assuming...
Please avoid SMS spelling in your messages on this forum.
❝ Thanks but will the same work for Non compartmental model also?
Let me replace multicompartmental with multiphasic, then ?
❝ And if you are so worried about including the time of distribution then the postulate of instantaneous distribution is violated
Why make such a postulate ? Look at the PK profiles first.
❝ And if u are assuming instantaneous distribution then one must take all time points after completion of infusion to avoid bias created by statistics of R2
1. F*** R2
2. I don't assume instantaneous distribution or monophasic elimination without looking at the PK profiles for each subject.
(Also look at Helmut's first message in this same thread).
Regards
Ohlbe
—
Regards
Ohlbe
Regards
Ohlbe
Complete thread:
- Methods for calculation of half lives d_labes 2008-02-01 14:58 [NCA / SHAM]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Methods for calculation of half lives Helmut 2008-02-01 16:59
- Methods for calculation of half lives Ohlbe 2008-02-02 23:00
- Minimum AIC?! Helmut 2008-02-03 13:49
- G (Kinetica) = R²adj (WinNonlin) Helmut 2008-02-04 01:12
- Minimum AIC?! Helmut 2008-02-03 13:49
- Methods for calculation of half lives d_labes 2008-02-04 16:43
- MAIC and beyond... Helmut 2008-02-04 17:49
- Methods for calculation of half lives Ohlbe 2008-02-02 23:00
- TTT method Helmut 2008-05-10 13:56
- TTT method d_labes 2008-05-16 09:12
- TTT method Helmut 2008-05-16 17:21
- TTT method d_labes 2008-05-23 15:43
- TTT method hiren379 2012-07-11 11:11
- TTT method Ohlbe 2012-07-11 11:37
- TTT method hiren379 2012-07-11 11:44
- TTT methodOhlbe 2012-07-11 12:16
- TTT method hiren379 2012-07-11 12:53
- Eyeball-PK Helmut 2012-07-11 14:37
- Eyeball-PK hiren379 2012-07-11 15:28
- Eyeball-PK Helmut 2012-07-11 15:47
- Eyeball-PK hiren379 2012-07-11 16:24
- Eyeball-PK Helmut 2012-07-11 15:47
- Eyeball-PK hiren379 2012-07-11 15:28
- Eyeball-PK Helmut 2012-07-11 14:37
- TTT method hiren379 2012-07-11 12:53
- TTT methodOhlbe 2012-07-11 12:16
- TTT method hiren379 2012-07-11 11:44
- TTT method Ohlbe 2012-07-11 11:37
- TTT method hiren379 2012-07-11 11:11
- TTT method d_labes 2008-05-23 15:43
- TTT method Helmut 2008-05-16 17:21
- TTT method d_labes 2008-05-16 09:12
- Methods for calculation of half lives Helmut 2008-02-01 16:59
Ing. Helmut Schütz