Bioequivalence and Bioavailability Forum

Several group design with unequal washout [Design Issues]

posted by sarawut – Thailand, 2012-05-08 18:49 (5147 d 11:23 ago) – Posting: # 8536
Views: 6,943

Dear Helmut,

Thanks for your response.
Personally, I have seen the study with 2 equal groups because of the limitation of facility. That is reasonable coz to handle more than 24 subjects at the same day is quite tough.
However for this study, I am just curious that why they didn't try to a maxium capacity of their facility. The number of subjects in each 5 groups are not the same.
Each subject could have washout interval for 7, 8, 9, 10 days. I have just seen it.

But it seem OK if there is no group effect.

Sarawut

Complete thread:

• Several group design with unequal washout sarawut 2012-05-08 12:36 [Design Issues] 
  • Several group design with unequal washout Helmut 2012-05-08 13:40
    • Hidden Q? d_labes 2012-05-08 15:02
      • Q unveiled Helmut 2012-05-08 15:38
        • Q or not Q ? Ohlbe 2012-05-09 11:15
          • "." ≠ "?" Helmut 2012-05-09 12:28
    • Several group design with unequal washoutsarawut 2012-05-08 16:49
      • Several group design with unequal washout boonchai_l 2012-05-16 12:19
        • Thai FDA Helmut 2012-05-16 13:01
          • Thai FDA boonchai_l 2012-05-16 13:37
            • Thai FDA Helmut 2012-05-16 13:55
              • Thai FDA boonchai_l 2012-05-16 19:02
                • Thai FDA ElMaestro 2012-05-21 23:45
              • Thai FDA boonchai_l 2012-05-21 12:05
  • Several group design with unequal washout sarawut 2012-06-05 06:02