Bioequivalence and Bioavailability Forum

Hi HS,

❝ What do you think?

A wise guy at the CRO probably got the brilliant idea to write a script that does the linear regression from the first points after Tmax and onwards.
This is a brilliant idea for several reasons:

1. All molecules, across all therapeutic classes in all humans subjects are eliminated in a first-order fashion. We all know that. Higher order elimination is free fantasy, like gnomes or eskimoes.
   
2. All molecules are polite. They wait patiently until all their fellow molecules have been absorbed into the blood stream before they commit themselves to elimination.
   
3. A script saves time and money; it takes a computer 2/10000000 of a second to do the calculation and you do not have to apply any degree of common sense or other processes that involve thinking or other resource-intensive activity.

Probably the wise guy has already been promoted as we speak?