Bioequivalence and Bioavailability Forum

Integration - smoothing [Bioanalytics]

posted by moblak – 2010-11-17 16:26 (5688 d 18:59 ago) – Posting: # 6156
Views: 12,116

Dear Helmut,

❝ You are aware that you never use the raw signal of the detector?

That's why I wrote "raw" data.

❝ See also this spring’s discussion at David’s PK-List.

A very nice discussion (thanks), but no closures for me

❝ Stupid question: A/P?

Accuracy/Precision

❝ orthogonal regression.

By clicking on the link I just got formulaphobia

❝ You can test the slope for # 1 and the intercept for # 0.

I am not sure what do you mean. Could you please explain in more detail?

Btw. Do you use smoothing for data processing of your LC-MS/MS chromatograms.

Regards
Marko

Complete thread:

• Integration - smoothing moblak 2010-11-17 11:46 [Bioanalytics] 
  • Integration - smoothing Helmut 2010-11-17 14:32
    • Integration - smoothingmoblak 2010-11-17 15:26
      • Integration - smoothing Helmut 2010-11-17 16:31
        • Integration - smoothing moblak 2010-11-18 14:39
          • Deming regression: example Helmut 2010-11-18 15:33
          • Jackknife Helmut 2010-11-18 18:35
            • Torture moblak 2010-11-19 09:25
              • Fun! Helmut 2010-11-19 13:47
            • Sharpen the Jackknife d_labes 2010-11-19 16:00
              • Sharpen the Jackknife Helmut 2010-11-19 16:19
  • Integration - smoothing Ohlbe 2010-11-18 01:39
    • Integration - smoothing moblak 2010-11-18 10:57
      • ANVISA Ohlbe 2010-11-18 13:58