Bioequivalence and Bioavailability Forum

Dear HS,

Thanks for your prompt reply,

Actually this question related to serum analysis. and Sponsor interested, to check if any change from baseline values and treatment values (decrease in values or not)?
They ask me to calculate maximum decrease in serum concentration (somewhere middle of sampling hour this value comes) and time of max. decrease.

I don't have data but following are expected data values.

e.g. for subj 1
time point:            0    2    4    6    8   10   12   14   16   18   20
serum concentration:  20.6 16.5 14.2 10.8  7.3  5.6  9.7 12.9 15.3 18.4 21.5

Kindly go through it,

waiting for your valuable comment.

Ram