Bioequivalence and Bioavailability Forum • Not positive about that

Not positive about that [Nonparametrics]

posted by martin – Austria, 2010-09-16 23:00 (5751 d 07:50 ago) – Posting: # 5922
Views: 27,099

Dear HS!

thank you for your point of view, I just have a minor comment regarding the interpretation of relative effects. It's a probability that a randomly selected subject with R has a larger t_max value than a randomly selected subject with T (no effect would be indicated by a relative effect of 0.5).

for the given dataset, the probability of a randomly selected subject with R having a larger t_max value than a randomly selected subject with T is 63.3% (90% CI: 35.4% to 84.4%).

the other way round, the probability of a randomly selected subject with T having a smaller t_max value than a randomly selected subject with R is 63.3% (90% CI: 35.4% to 84.4%).

best regards

martin

PS.: this is a naive application to the dataset - some adjustments may necessary to account for the cross over design

Complete thread:

tmax in case of ties: R vs. R vs. SAS d_labes 2010-09-10 12:05 [Nonparametrics]
- tmax in case of ties: StatXact, Phoenix, and... Helmut 2010-09-10 18:28
  - Ties, no ties, ties, no ties ... d_labes 2010-09-13 13:21
    - simulation martin 2010-09-14 08:33
      - simulants of the world unite d_labes 2010-09-15 10:14
        
        simulants of the world unite martin 2010-09-15 14:53
        
        simulants of the world unite Helmut 2010-09-15 16:17
        
        simul ants with no ties d_labes 2010-09-16 11:19
        
        simul ants with no ties Helmut 2010-09-16 14:01
        
        two different approaches martin 2010-09-16 15:35
- evaluation of tmax: use of relative effects? martin 2010-09-16 18:04
  - Not positive about that Helmut 2010-09-16 19:52
    - Not positive about thatmartin 2010-09-16 21:00
      - Stupidity Helmut 2010-09-17 13:10
- tmax in case of ties: R vs. R vs. SAS Jack 2010-09-20 14:03
  - R packages Helmut 2010-09-20 14:20
    - R packages code d_labes 2010-09-27 11:27
    - R packages Jack 2010-09-27 16:14
  - Is Exact exact? d_labes 2010-09-27 09:53