Donepezil SR 23 mg Tablets BE study [Study Per­for­mance]

posted by Dr. Solanki – 2010-08-12 13:30 (5780 d 09:35 ago) – Posting: # 5772
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Dear Members,

Further to my last communication, I am expecting some comments/views from members on the subject. I also thought of a major risk of aspiration bronchopneumonia if the fed study is performed as multi-dose, steady-state in elderly pts. Most eligible pts for the study would be above 60.

Hence, it is even better to opt for the required fasted & fed studies in HHVs
under an apropriately chosen antiemetic. Ondansetron, dimenhyrinate, meclizine, promethazine, etc. have shown no interaction upon reviewing the litt.

Comments from other members pls.. including special request to Helmut.

Rgds,

Dr. Solanki
MD (Pharmacology)

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