Proc MIXED CV%-intra, CV%-inter [General Sta­tis­tics]

posted by kvitamin – Hungary, 2009-10-07 18:15 (6085 d 21:20 ago) – Posting: # 4317
Views: 38,093

Dear D_Labes,

Thank you very much for your help.
I apply the SAS proc mixed because this procedure is assessed in FDA's guidance and I want to learn how works it (it is not simple).

If I have a study data set as Helmuts data with 52 subjects and I calculate
intra-CV and inter-CV based on your help, I will get results for all the subjects not for subjects in group T or subjects in group R, separately.

For example, if I want to calculate inter-subject CVs for T and R formulations then intra-subject CV, how can I calculate them from the covariance parameter output? There stand only two values (as it was presented by your answer) and I need three results, eg for lognormal AUC0-t:

AUC0-t A inter-CV(?) 
         intra-CV(?)
       B inter-CV(?)


Thank you!

kvitamin


Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post!
PS: Which dataset of mine with 52 subjects are you talking about? [Helmut]

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