Bioequivalence and Bioavailability Forum

All the important answers are here! [🇷 for BE/BA]

posted by ElMaestro  – Denmark, 2009-09-28 21:12 (5316 d 22:15 ago) – Posting: # 4261
Views: 39,014

Dear HS,

❝ Oh, I took these boots on many years ago. And they got muddy almost immediatelly. I tried to get a numerical approximation of the cdf of the t-distribution which lead me to the gamma-function and headaches.

❝ Finally I ended up with numerical approximations.^[1,2]

Let me highfive you for this. I did the same, in C, and it took me quite some time, only to find out later that C actually comes with a beautiful function called lgamma which does it and returns the logarithm. I wasted a good part of my youth reinventing the wheel it seems

❝ BTW, nitpicking Diletti’s Table 1^[6] (power 70%, T/R=1, CV=7.5%) and nQuery 7 give n=4, whilst my R code, StudySize 2.0.1, and FARTSSIE 1.6 come up with n=6. Now what? Go with a democratic vote of 3:2 for 6?

Two solutions:

1. Ask dlabes
   
2. Get your power from a program that bases its evaluation on brute force rather than on numerical integration.

EM.

Complete thread:

• R-Code for Power in 2×2 Cross-over Helmut 2006-12-28 21:33 
  • Power in Diletti's sample size table Helmut 2007-01-01 23:59
    • Approximate Power Helmut 2007-01-06 15:17
      • Power Calculation for replicate crossover design mathews 2008-04-03 13:19
        • Power Calculation for replicate crossover design Helmut 2008-04-03 13:49
          • Power Calculation for replicate crossover design mathews 2008-04-04 13:21
      • Exact Power Helmut 2009-09-25 19:20
        • Exact Power ElMaestro 2009-09-27 23:27
          • Software validation Helmut 2009-09-28 15:21
            • All the important answers are here!ElMaestro 2009-09-28 19:12
              • All the important answers are here! Helmut 2009-09-28 19:52
                • All the important answers are here! ElMaestro 2009-09-28 20:18
                • All the important answers are here! yjlee168 2009-09-28 21:30
                  • All the important answers are here! Helmut 2009-09-28 23:18
                    • 42! SASophylistic power oracle d_labes 2009-09-29 13:37
                      • Al Gore Rhythms Helmut 2009-09-29 14:52
                        • Al Gore Rhythms ElMaestro 2009-09-29 18:14
                        • Al Gore Rhythms yjlee168 2009-09-29 23:55
                  • All the important answers are here! yjlee168 2009-09-29 23:49
  • R-Code for Power in 2×2 Cross-over KDA 2019-01-23 04:24
    • R-Code for Power in 2×2 Cross-over Ohlbe 2019-01-27 18:24
  • R-Code for Power in 2×2 Cross-over Brus 2021-12-02 15:00
    • R-Code for Power in 2×2 Cross-over ElMaestro 2021-12-02 15:15
      • R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 17:30
    • R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 16:57