R2-adj, cut-off [PK / PD]

posted by Helmut Homepage – Vienna, Austria, 2009-04-23 16:39 (6257 d 05:53 ago) – Posting: # 3593
Views: 12,000

Dear Raveendra!

❝ […] what is the minimum R2 value […]. some are using 0.8 and some are using 0.75. which one correct?


Neither nor, because R² depends on the number of data points used in the estimation. In linear regression R² 0.9756 (n=3) ‘explains’ the same amount of information as R² 0.5314 (n=6)!
For a rather lengthy discussion see this thread.
If you truly want to set a cut-off, then R²adj should be used. BTW a cut-off common to all studies is not justified. For drug A a R²adj of 0.95 may be easy to get, whilst for drug B a R²adj of even 0.75 very difficult.

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