Bioequivalence and Bioavailability Forum • SAS and WinNonlin

SAS and WinNonlin [Software]

posted by Helmut – Vienna, Austria, 2008-12-12 17:33 (6052 d 03:45 ago) – Posting: # 2919
Views: 33,305

Dear D. Labes,

thanks for SAS' output!

❝ Seems 'Method of moments' is used here?

Yes – but only to get initial variance estimates.

❝ With the exception of lambda(1,1) there seems no match :-( !

Yes.

❝ Now we need someone with knowledge of relationship of SAS and WINNONLIN parameters.

We should wait for Simon Davis coming by (he has also experience with SAS)...

❝ Is var(period*treatment*subject) the intra-subject variability?

Yes, well the variance (and you get the CV in the usual way; not built-in in WinNonlin: pocket-calculator business):
Var(period*treatment*subject)_21 sigma²_reference
Var(period*treatment*subject)_22 sigma²_test

—
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Helmut Schütz

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Complete thread:

SAS code of partial replicate design pa1kumar.anna 2008-12-01 09:51 [Software]
- Etiquette Ohlbe 2008-12-01 10:45
- SAS code for what? d_labes 2008-12-02 09:17
  - partial replicate = 3-period replicate Helmut 2008-12-03 15:42
    - partial replicate = 3-period replicate MGR 2008-12-04 11:19
    - 3-period replicate designs and SAS d_labes 2008-12-04 14:17
      - Extra-reference or partial replicate design d_labes 2008-12-12 10:51
        
        Extra-reference or partial replicate design Helmut 2008-12-12 11:34
        
        Simple minded d_labes 2008-12-12 13:28
        
        Simple minded Helmut 2008-12-12 14:58
        
        SAS and WinNonlin d_labes 2008-12-12 15:44
        
        SAS and WinNonlinHelmut 2008-12-12 16:33
        
        SAS and WinNonlin BEQool 2024-07-29 09:38
        
        Phoenix RSABE-template Helmut 2024-07-29 13:29
        
        Phoenix RSABE-template BEQool 2024-07-29 19:47
        
        CVw in Phoenix RSABE-template Helmut 2024-07-30 09:15
        
        CVw in Phoenix RSABE-template BEQool 2024-07-30 10:56
        
        CVw in Phoenix RSABE-template and PowerTOST CI2CV() Helmut 2024-07-30 11:23
        
        CVw in Phoenix RSABE-template and PowerTOST CI2CV() BEQool 2024-07-31 05:49
        
        General ABE? mittyri 2024-07-31 18:25
        
        General ABE? BEQool 2024-08-01 05:45
        
        Switchability and Prescribability in WinNonlin MGR 2008-12-30 10:12
        
        PBE and IBE in WinNonlin Helmut 2008-12-30 16:04
        
        PBE and IBE in WinNonlin MGR 2008-12-31 07:52
        
        Switchability NPavan 2009-01-12 13:10