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RegisterCalculation of AUC0-72 [NCA / SHAM]
Dear Ohlbe, dear Jaime, dear all,
I would like to discuss this a bit further.
How do you act in a truncated setting if the last sample is missing? Or if some subject has conc. <LOQ due to faster kinetics?
Omit this subject from the analysis? Or try to extrapolate to t=72h?
If extrapolation is an option for you: how?
Using an estimate of lamdaZ or by the last preceding 2 points?
I would like to discuss this a bit further.
How do you act in a truncated setting if the last sample is missing? Or if some subject has conc. <LOQ due to faster kinetics?
Omit this subject from the analysis? Or try to extrapolate to t=72h?
If extrapolation is an option for you: how?
Using an estimate of lamdaZ or by the last preceding 2 points?
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
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![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Calculation of AUC0-72 Jaime_R 2008-06-10 12:18
- Calculation of AUC0-72 Ohlbe 2008-06-10 17:28
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- Regulators truncated Ohlbe 2009-06-18 10:37
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- Regulators truncated ElMaestro 2009-06-19 22:16
- Regulators truncated Helmut 2009-06-19 22:35
- Regulators truncated ElMaestro 2009-06-19 22:16
- Regulators truncated Helmut 2009-06-18 15:44
- Regulators truncated d_labes 2009-06-18 15:26
- Luke 23:34 ElMaestro 2009-06-18 14:50
- Regulators truncated d_labes 2009-06-18 09:26
- Calculation of AUC0-72d_labes 2008-09-05 15:00
- Calculation of AUC0-72 Helmut 2009-01-26 16:24
- Calculation of AUC0-72 d_labes 2009-01-26 16:57
- Calculation of AUC0-72 Helmut 2009-01-26 17:20
- The missing 72h d_labes 2009-01-27 11:48
- The missing 72h Ohlbe 2009-01-28 00:00
- sensitivity analyses ? martin 2009-01-28 08:26
- Regulators ways are inscrutable d_labes 2009-01-28 09:54
- Regulators ways are inscrutable (at least the French) Ohlbe 2009-01-28 10:16
- The missing 72h ElMaestro 2009-01-28 14:32
- Page 3848 of 221 d_labes 2009-01-28 14:51
- Partial AUC calculation Astea 2017-03-11 20:14
- Partial AUC calculation mittyri 2017-03-16 19:46
- The missing 72h Ohlbe 2009-01-28 00:00
- The missing 72h d_labes 2009-01-27 11:48
- Calculation of AUC0-72 Helmut 2009-01-26 17:20
- Calculation of AUC0-72 d_labes 2009-01-26 16:57
- Calculation of AUC0-72 Helmut 2009-01-26 16:24
- Calculation of AUC0-72 Jaime_R 2008-06-10 18:45
- Calculation of AUC0-72 Ohlbe 2008-06-10 17:28
- Calculation of AUC0-72 PharmCat 2022-12-21 20:49
- Calculation of AUC0-72 Jaime_R 2008-06-10 12:18
Ing. Helmut Schütz