Bioequivalence and Bioavailability Forum • Sample Size Replicated Study

Sample Size Replicated Study [Power / Sample Size]

posted by Helmut – Vienna, Austria, 2008-08-18 13:57 (6510 d 06:32 ago) – Posting: # 2195
Views: 11,034

Dear Ashwini,

❝ Can we calculate the sample size for Replicate 3 period (ABB/BAA) & Replicate 4 period (ABBA/BAAB) on the basis of Intra CV got in 2way crossover study. Could you please tell me by what amount or percentage it will reduce for 3 way and 4 way crossover study.

Yes; see this post for TRT/RTR (75% of TR/RT) and TRRT/RTTR (50% of TR/RT).
No idea about TRR/RTT...

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Complete thread:

Sample Size Replicated Study ashwinim13 2008-08-18 10:42 [Power / Sample Size]
- Sample Size Replicated StudyHelmut 2008-08-18 11:57
  - Sample Size Replicated Study d_labes 2008-08-21 09:13
    - Sample Size Replicated Study Helmut 2008-08-21 12:25
- Sample Size Replicated Study vidulabhole 2012-01-31 08:11
  - 4-treatment-4-period study d_labes 2012-01-31 10:35
    - 4-treatment-4-period study vidulabhole 2012-01-31 13:15
      - Clinical study d_labes 2012-01-31 16:38