Evaluation of Heparin as a potentially interfering substance [Bioanalytics]

posted by nobody – 2019-09-11 21:32 (1685 d 19:38 ago) – Posting: # 20586
Views: 2,669

Heparin is a polyanion, so: Calculate the amount instilled, the volume of fresh blood used to "flush" this amount to the blood collecting device, the resulting concentration in the blood/plasma sample. Use common sense to asses these numbers.

If in doubt (due to physico-chemical properties of analyte), do some in vitro studies with fresh blood/heparin.

Kindest regards, nobody

Complete thread:

UA Flag
Activity
 Admin contact
22,991 posts in 4,827 threads, 1,647 registered users;
63 visitors (1 registered, 62 guests [including 8 identified bots]).
Forum time: 17:10 CEST (Europe/Vienna)

If you don’t like something change it;
if you can’t change it, change the way you think about it.    Mary Engelbreit

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5