Intrasubject CV for fed studies [PK / PD]

posted by ElMaestro  – Belgium?, 2019-08-22 19:56 (353 d 09:44 ago) – Posting: # 20507
Views: 1,489

Hi jag,

» Does anyone know if it is possible to estimate the intrasubject CV of a drug for a fed study if only the food effect data is available (and fasting BE study data)?

It is not readily possible. Both a negative and a positive food effect can be accompanied by a decreased or increased CV. You'll need to work hard for this one :crying:

I could be wrong, but...

Best regards,
ElMaestro

"Pass or fail" (D. Potvin et al., 2008)

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