Tmax and T1/2 [NCA / SHAM]

posted by Ohlbe – France, 2008-07-15 12:33 (6538 d 21:17 ago) – Posting: # 2036
Views: 24,664

Dear Alhas,

The body does not press a button at Tmax to stop absorbing the drug and to start eliminating it. Elimination starts at the second the drug enters the body. Tmax is the time when you reach a balance between absorption and elimination: before Tmax the drug enters the body faster than it is eliminated, and concentrations increase. After Tmax the drug is eliminated faster than it is absorbed, and concentrations decrease.

Regards
Ohlbe

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