Graphing Mean PK profile [R for BE/BA]

posted by nobody – 2019-04-24 12:15  – Posting: # 20226
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» Some people set all BQLs to zero in order to calculate the arithmetic mean. Others set the first BQL after tmax to LLOQ/2, and, and, and… There will always be a bias.

How would you otherwise calculate the geo. mean profile?

And AUCtlast is a mess with different tlast for T and R and and and. Statistics is always some kind of abstraction. Do a spaghetti plot for T and R and individual T+R for each subject and you might get completely different "ideas" / insights...

Kindest regards, nobody

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