Larger difference between upper and lower limit of 90% CI [Power / Sample Size]

posted by mirza baig  – Mumbai, India, 2018-11-28 16:14  – Posting: # 19654
Views: 1,736

Hello Everyone,

I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).


Response will be highly appreciated


Edit: category changed [Ohlbe]

Complete thread:

Activity
 Admin contact
20,793 posts in 4,353 threads, 1,445 registered users;
online 4 (0 registered, 4 guests [including 4 identified bots]).
Forum time: 23:41 CEST (Europe/Vienna)

Genius is that which forces
the inertia of humanity to learn.    Henri Bergson

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5