Bioequivalence and Bioavailability Forum 19:41 CET

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Old belives die hard [General Sta­tis­tics]

posted by d_labes - Berlin, Germany, 2018-07-04 13:28  - Posting: # 19020
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Dear Detlew,

» » IMHO we don't need an alpha correction for your case above, if we combine the tests with 'and'.
» THX for reminding me (not for the first time)…

Correct.
But old belives die hard :-D

» » Eventually we can miss-use power.2TOST() ...
» » Then of course the question of the correlation parameter rho arises. How to choose?
» Not sure. Whereas two PK metrics are always correlated somehow, IMHO, here it may be different. One formulation doesn’t care how it behaves in relation to the other...

Sounds for me like rho=0 :cool:.

Regards,

Detlew

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