Decision of confidence interval of three period BE study [General Sta­tis­tics]

posted by libaiyi – China, 2018-06-26 12:00 (820 d 13:08 ago) – Posting: # 18964
Views: 9,457

(edited by Ohlbe on 2018-06-26 12:24)


I am curious of the confidence interval decision of three treatment, three sequences, cross over BE study as below, if the goal is to prove the equivalence of any two of them (T1 and R or T2 and R). Will the CI still determined as 95% or 90%?

Sequence/Period  1  2  3 
      1          R  T1 T2
      2          T1 T2 R 
      3          T2 R  T1

I also want to know how to select the suitable design between latin squares and William design when there exists three treatment, R T1 T2.

Thanks in advance.:-D

Edit: two posts merged. You can edit your message up to 24 hours after posting it [Ohlbe]

Complete thread:

 Admin contact
21,072 posts in 4,394 threads, 1,468 registered users;
online 3 (0 registered, 3 guests [including 3 identified bots]).
Forum time: Thursday 01:08 CEST (Europe/Vienna)

Enlightenment is man’s emergence from his self-imposed nonage
for which he himself was responsible.
Nonage is the inability to use one’s own intellect
without the direction of another.    Immanuel Kant

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz