Bioequivalence and Bioavailability Forum • ...and apart from that Perindopril is a difficult analyte

...and apart from that Perindopril is a difficult analyte [Regulatives / Guidelines]

posted by Ohlbe – France, 2018-05-18 17:26 (2162 d 16:30 ago) – Posting: # 18783
Views: 2,916

Dear El Maestro,

❝ [...] and any conversion to perindoprilat in plasma can be easily controlled.

But beware of the back-conversion of the acylglucuronides, both of perindopril and of perindoprilat. They are well known for their instability. Some people have run into trouble.

—
Regards
Ohlbe

Complete thread:

is Perindoprilat optional? mittyri 2018-05-17 22:47
- Need to know vs. nice to know Helmut 2018-05-18 12:35
  - where nice to know is mandatory mittyri 2018-05-19 23:46
- ...and apart from that Perindopril is not a difficult analyte ElMaestro 2018-05-18 14:26
  - ...and apart from that Perindopril is a difficult analyteOhlbe 2018-05-18 15:26