Bioequivalence and Bioavailability Forum 02:43 CET

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...and apart from that Perindopril is a difficult analyte [Regulatives / Guidelines]

posted by Ohlbe - France, 2018-05-18 15:26  - Posting: # 18783
Views: 904

Dear El Maestro,

» [...] and any conversion to perindoprilat in plasma can be easily controlled.

But beware of the back-conversion of the acylglucuronides, both of perindopril and of perindoprilat. They are well known for their instability. Some people have run into trouble.

Regards
Ohlbe

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