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Back to the forum  Query: 2018-02-21 11:54 CET (UTC+1h)
 

Hammer to fall [General Sta­tis­tics]

posted by Astea - Russia, 2018-02-12 18:37  - Posting: # 18408
Views: 949

Dear all!

They say that upon hearing that one of his students had dropped out to study poetry David Hilbert said: "Good, he did not have enough imagination to become a mathematician".


Dear Detleww!

» In that light 0.050024 is of course not an alpha-inflation. As we know from theory, the IUT » principle, the combination of two TOST via and assures alpha<=0.05. Thus interpret the result as 0.05. Full stop

Thank you very much for clarification! So then it's just a numeric atavism and misinterpretation.


Dear Helmut!

» Get a faster machine!
I've got one, but currently my car do not provide calculations in PowerTost :-)

I may suppose there were some problems in your Acetylsalicylic acid study - may be in stability or inadequate sampling time, did you measure also salicylic acid? What was the dose? Below are my results on ASA study (data of reference drug only): rho is 0.667, 95% CI: [0.361; 0.844]. For Test+Ref data rho is about 0.755.

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