Bioequivalence and Bioavailability Forum • PK parameters from multiple doses

PK parameters from multiple doses [PK / PD]

posted by SDavis – UK, 2017-11-24 10:59 – Posting: # 18000
Views: 6,020

I would echo Helmut's comments regarding the assumptions you would have to make and convey to your audience; probably I would try to build a compartmental PK model and then simulate a profile for Day 1.

Simon

—
Simon
Senior Scientific Trainer
Pharsight - A Certara™ Company
Simon Davis at LinkedIn
https://www.certara.com/training/training-your-way
https://support.certara.com/forums/
Problems are not stop signs, they are guidelines. Robert H. Schuller

Complete thread:

Single PK parameters from multiple PK parameters asjrm 2017-11-19 00:44
- Single PK parameters from multiple PK parameters jag009 2017-11-19 06:32
- PK parameters from multiple doses Helmut 2017-11-19 10:24
  - PK parameters from multiple doses Yura 2017-11-21 11:48
  - PK parameters from multiple dosesSDavis 2017-11-24 10:59
    - PK parameters from multiple doses nobody 2017-11-24 16:07
      - PK parameters from multiple doses SDavis 2017-11-24 22:09
        
        PK parameters from multiple doses nobody 2017-11-27 14:13
        
        PK parameters from multiple doses SDavis 2017-11-28 11:34
        
        PK parameters from multiple doses nobody 2017-11-28 11:51
        
        PK parameters from multiple doses SDavis 2017-11-28 11:54
- Single PK parameters from multiple PK parameters nobody 2017-11-21 14:54