Single PK parameters from multiple PK parameters [PK / PD]

posted by nobody – 2017-11-21 13:54  – Posting: # 17998
Views: 6,131

Assuming you are in steady-state on day 15 (and linear PK/no induction, of course), the AUC over the dosing interval on Day 15 should equal the AUC0-oo of a single dose.

To estimate the Cmax following single-dose you would need to sample on Day 1 imho...

Kindest regards, nobody

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