PK parameters from multiple doses [PK / PD]

posted by Yura – Belarus, 2017-11-21 11:48  – Posting: # 17997
Views: 6,125

Hi Helmut
AUC is truncated with an interval of reception (in the morning and in the evening - 12 hours).
what 24 hours? if after the first dose - it is also 12 hours. Perhaps, the AUCt / AUCi criterion will be less than 80%.
Thank you

Complete thread:

Activity
 Admin contact
20,250 posts in 4,262 threads, 1,397 registered users;
online 20 (0 registered, 20 guests [including 7 identified bots]).
Forum time (Europe/Vienna): 18:43 CET

Many people tend to look at programming styles and languages like religions:
if you belong to one, you cannot belong to others.
But this analogy is another fallacy.    Niklaus Wirth

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5