PK parameters from multiple doses [PK / PD]

posted by Yura – Belarus, 2017-11-21 11:48 (996 d 06:25 ago) – Posting: # 17997
Views: 7,171

Hi Helmut
AUC is truncated with an interval of reception (in the morning and in the evening - 12 hours).
what 24 hours? if after the first dose - it is also 12 hours. Perhaps, the AUCt / AUCi criterion will be less than 80%.
Thank you

Complete thread:

Activity
 Admin contact
21,015 posts in 4,380 threads, 1,460 registered users;
online 18 (0 registered, 18 guests [including 13 identified bots]).
Forum time: Thursday 19:13 CEST (Europe/Vienna)

If you obey all the rules,
you will miss all the fun.    Katharine Hepburn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5