calculation of 90% CI for continuous variable in clinical endpoint studies [General Sta­tis­tics]

posted by GM – India, 2017-11-17 05:55 (2323 d 21:18 ago) – Posting: # 17986
Views: 5,611

Hello All,

As I am new to the endpoint studies, how can we calculate 90% CI for continuous variable in clinical endpoint studies?

As per my understanding, there are two ways. One is ±20 rule for the difference of means and 80-120% rule for ratio of means of un-transformed data. Based on this reference 90% CI Calculation

But as per OGD, the 90%CI should lies in 80-125% for un-transformed data. Please see the point no.21 in the OGD (see Clindamycin Phosphate).

This is :confused: me a lot. Please clarify.


Edit: URL corrected. Please don’t link to a Google-India search term. [Helmut]

Best Regards,
GM

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
86 visitors (0 registered, 86 guests [including 3 identified bots]).
Forum time: 03:13 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5