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A place to start [Two-Stage / GS Designs]

posted by ElMaestro - Denmark, 2017-11-12 21:43  - Posting: # 17973
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Hi Hötzi,

can you run a series of sims where you include "20 more subjects than necessary" in stage 2 where a stage 2 is called for?
Just to see how things look from that perspective.

if (3) 4

Best regards,
ElMaestro

"(...) targeted cancer therapies will benefit fewer than 2 percent of the cancer patients they’re aimed at. That reality is often lost on consumers, who are being fed a steady diet of winning anecdotes about miracle cures." New York Times (ed.), June 9, 2018.

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