Vd/F calculation in bear [R for BE/BA]
You are right, I meant 2.6.2. Sorry for the brain fart.
» What was your selection for trapezoidal method?
linear-up/log-down(default method) or
all linear? That could make a little differences.
My selection was default
» [...] What about Cl/F?
Now That I looked for teh code as Helmut told me is all very clear. It seems however that both Vd/F and Cl/F are affected by the same misscalculation from AUC0inf. I will check with the other methods and tell you later.
Anyway, your answers were very helpful. Many thanks