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Vd/F calculation in bear [R for BE/BA]

posted by CECIF - Colombia, 2017-11-03 23:54  - Posting: # 17968
Views: 1,988

» uhh... since version 6.2? bear? the current version is 2.8.3 (as shown in my signature panel).

You are right, I meant 2.6.2. Sorry for the brain fart. :-(


» What was your selection for trapezoidal method? linear-up/log-down (default method) or all linear? That could make a little differences.

My selection was default


» [...] What about Cl/F?


Now That I looked for teh code as Helmut told me is all very clear. It seems however that both Vd/F and Cl/F are affected by the same misscalculation from AUC0inf. I will check with the other methods and tell you later.

Anyway, your answers were very helpful. Many thanks

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