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CI equation for 4 Period, 2 sequences "Full Replicate" [RSABE / ABEL]

posted by Mohamed Yehia - Egypt, 2017-10-29 17:00  - Posting: # 17941
Views: 840

Dear All,

I want to know the equation used to calculate the CI for 4 period, 2 sequences BE study using sequences:

Seq1: TRTR
Seq2: RTRT

According to my knowledge the Degree of Freedom used in the equation is (n1+n2)-2. However, I am afraid that the DF shall be 3n-4. So, which one shall I use

Thanks.

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