Bioequivalence and Bioavailability Forum

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log-in |  Register |  Search

Back to the forum  Query: 2017-10-21 03:01 CEST (UTC+2h)
 

Correct Isotope Enrichment from %Assay Calculation for Internal Standard [Bioanalytics]

posted by TK - Thailand, 2017-10-04 11:39  - Posting: # 17847
Views: 235

Dear All,

One of our client give us a comment that we should correct %isotope enrichment from %assay calculation of stable labelled isotope to get more accuracy for %assay value. However, we think that it is not necessary to do it that way as we add same amount of internal standard in single reaction so that this will not have any impact on quantitation.

I would like to hear opinion from the experts in BE/BA forum.

Will we need to correct %isotope enrichment from %assay calculation of internal standard?

Thank you so much!

TK


Edit: Category changed; see also this post #1. [Helmut]

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum | Admin contact
17,396 Posts in 3,726 Threads, 1,074 registered users;
24 users online (0 registered, 24 guests).

The difference between a surrogate and a true endpoint
is like the difference between a cheque and cash.
You can get the cheque earlier but then,
of course, it might bounce.    Stephen Senn

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
XHTML/CSS RSS Feed