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RegisterOdd QC values but not outliers [Bioanalytics]
Hello Thi Nguyen,
can you:
1. Indicate if the same sample no from run 2 was also one of the affected samples in run 1? (I mean if the affected sample in run 2 was "sample 17" then check if "sample 17" was also funky in run 1 etc)
2. Post bits of the result table, in particular indicate if the aberrant result for certain sample arose out of a fluke in the area of the analyte itself, or due to a low IS response, or possibly both?
3. Tell if the RTs in analyte and IS was more or less the same for affected samples and unaffected samples?
4. Eyeball the integration and check of you feel it was correct? Sometimes, at LLOQs depending on noise and bunching and a ton of factors that I know very little about, the actual interpolated baseline under the analyte chromatogram is visibly off and this in itself can give rise to some seriously deviating areas.
5. Check if the chromatograms are rugged, peaks-on-peaks etc.
can you:
1. Indicate if the same sample no from run 2 was also one of the affected samples in run 1? (I mean if the affected sample in run 2 was "sample 17" then check if "sample 17" was also funky in run 1 etc)
2. Post bits of the result table, in particular indicate if the aberrant result for certain sample arose out of a fluke in the area of the analyte itself, or due to a low IS response, or possibly both?
3. Tell if the RTs in analyte and IS was more or less the same for affected samples and unaffected samples?
4. Eyeball the integration and check of you feel it was correct? Sometimes, at LLOQs depending on noise and bunching and a ton of factors that I know very little about, the actual interpolated baseline under the analyte chromatogram is visibly off and this in itself can give rise to some seriously deviating areas.
5. Check if the chromatograms are rugged, peaks-on-peaks etc.
—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Odd QC values but not outliers Thi Nguyen 2017-09-18 14:43
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Odd QC values but not outliers Ohlbe 2017-09-18 15:53
- Odd QC values but not outliers Thi Nguyen 2017-09-19 13:14
- Odd QC values but not outliersElMaestro 2017-09-19 13:38
- Odd QC values but not outliers Ohlbe 2017-09-19 13:49
- Odd QC values but not outliers Thi Nguyen 2017-09-19 13:14
- Odd QC values but not outliers Ohlbe 2017-09-18 15:53
Ing. Helmut Schütz