Bioequivalence and Bioavailability Forum • forced BE?

forced BE? [Design Issues]

posted by Helmut – Vienna, Austria, 2017-08-07 16:00 (2451 d 01:39 ago) – Posting: # 17669
Views: 15,301

Hi ElMaestro,

❝ That is indeed why we need to apply more bootstrapping in BE.

Duno whether we need it. Of course, one can do it since the GL only speaks about “an appropriate sample size calculation.” Whatever that might be.

❝ It, too, tells what sample size we need, but in contrast to ordinary power calcs it allows one to take into account that residuals may not be normal even though the evaluation itself makes that assumption.

Right. But IMHO, the quality of bootstrapping depends on the input. Remember what you once wrote?

OT: In your current signature you claim to have “an affair with the bootstrap”. Really an affair? I mean, does it respond to your love? Or is it just calf love?

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Complete thread:

General BE topics VSL 2017-06-05 20:34 [Design Issues]
- General BE topics ElMaestro 2017-06-06 00:20
- General BE topics Helmut 2017-06-06 14:24
  - General BE topics VSL 2017-06-06 19:34
    - General BE topics DavidManteigas 2017-06-12 12:35
      - forced BE? Helmut 2017-08-04 15:51
        
        forced BE? DavidManteigas 2017-08-07 12:42
        
        forced BE? Helmut 2017-08-07 13:31
        
        forced BE? ElMaestro 2017-08-07 13:44
        
        forced BE?Helmut 2017-08-07 14:00
        
        forced BE? ElMaestro 2017-08-07 15:58
        
        forced BE? DavidManteigas 2017-08-07 14:02
        
        forced BE? Helmut 2017-08-07 14:26