Bioequivalence and Bioavailability Forum • sample size in bioequivalence studies

sample size in bioequivalence studies [Power / Sample Size]

posted by daryazyatina – Ukraine, 2017-08-03 12:08 (2451 d 12:17 ago) – Posting: # 17648
Views: 18,755

Hi, BE-proff. Thank you for your answer.

❝ Results must be different because PowerTOST uses iterative method for calculation.

Have you looked at the formula what I used? There is also used an iterative method.

❝ AFAIK, PowerTOST is used worldwide and no claims from regulators have been received.

It's good. But I asked another question.
I used formula from book:

❝ ❝ Shein-Chung Chow, Jun Shao and Hansheng Wang "Sample size calculations in clinical research" Copyright © 2003 by Marcel Dekker (Chapter 10. Bioequivalence Testing)

and also any claims from regulators have not been received.

Complete thread:

sample size in bioequivalence studies daryazyatina 2017-08-03 09:34
- sample size in bioequivalence studies BE-proff 2017-08-03 09:55
  - sample size in bioequivalence studiesdaryazyatina 2017-08-03 10:08
- sample size in bioequivalence studies ElMaestro 2017-08-03 10:17
  - sample size in bioequivalence studies daryazyatina 2017-08-03 10:58
    - sample size in bioequivalence studies DavidManteigas 2017-08-03 12:40
      - sample size in bioequivalence studies daryazyatina 2017-08-03 13:46
      - Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 15:37
        
        Don’t use the formula by Chow, Shao, Wang! daryazyatina 2017-08-03 15:52
        Don’t use the formula by Chow, Shao, Wang! DavidManteigas 2017-08-03 16:12
        
        Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 16:33
        
        Don’t use the Book by Chow, Shao, Wang! d_labes 2017-08-16 16:01
    - compromised power Helmut 2017-08-03 16:04
      - compromised power daryazyatina 2017-08-04 08:15
        
        terminology Helmut 2017-08-04 12:41
        
        terminology daryazyatina 2017-08-16 10:12
        
        terminology Helmut 2017-08-16 18:54
- sample size in bioequivalence studies balinskyi 2018-06-03 12:58

Admin contact
22,988 posts in 4,825 threads, 1,654 registered users;
104 visitors (0 registered, 104 guests [including 6 identified bots]).
Forum time: 00:26 CEST (Europe/Vienna)

The only way to comprehend what mathematicians mean by Infinity
is to contemplate the extent of human stupidity. Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC

Ing. Helmut Schütz