AUC calculation in bear [🇷 for BE/BA]
Hi all,
I have just started using bear. Thanks to the developers for this wonderful freeware.
Following is the AUC calculation done in bear for one subject data.
Now if i do manual calculation of AUC by trapezoid rule by formula, AUC is coming to 1478.681 instead of 1435.682 by bear.
Can anyone pls explain the reason for this difference.
Regards
Pjs
Edit: BBcoded; see also this post #6. [Helmut]
I have just started using bear. Thanks to the developers for this wonderful freeware.
Following is the AUC calculation done in bear for one subject data.
subj time conc AUC(0-t) AUMC(0-t)
1 0.00 0.000 0.000 0.000
1 1.00 0.000 0.000 0.000
1 1.50 0.000 0.000 0.000
1 2.00 0.000 0.000 0.000
1 2.50 0.000 0.000 0.000
1 3.00 0.000 0.000 0.000
1 3.50 0.000 0.000 0.000
1 4.00 1.518 0.380 1.518
1 4.33 5.027 1.459 6.111
1 4.67 12.700 4.473 19.894
1 5.00 22.210 10.233 48.004
1 5.33 18.013 16.846 82.120
1 5.67 22.332 23.704 119.967
1 6.00 30.500 32.422 171.055
1 6.33 24.290 41.423 226.493
1 6.67 31.676 50.937 288.549
1 7.00 32.647 61.551 361.117
1 7.50 45.512 81.091 503.584
1 8.00 95.827 116.425 780.573
1 10.00 120.261 332.513 2749.799
1 12.00 89.598 540.870 5031.520
1 16.00 41.572 791.036 8470.430
1 24.00 24.576 1049.699 13553.463
1 36.00 9.237 1237.802 19015.333
1 48.00 4.897 1319.870 22410.463
1 72.00 1.976 1397.115 26906.872
1 96.00 1.287 1435.682 30113.526
Now if i do manual calculation of AUC by trapezoid rule by formula, AUC is coming to 1478.681 instead of 1435.682 by bear.
Can anyone pls explain the reason for this difference.
Regards
Pjs
Edit: BBcoded; see also this post #6. [Helmut]
Complete thread:
- AUC calculation in bearpjs 2017-05-21 15:57 [🇷 for BE/BA]
- lin-up/log-down is bear’s default Helmut 2017-05-21 17:32
- lin-up/log-down any regulatory recommendation? pjs 2017-05-21 19:08
- lin-up/log-down any regulatory recommendation? Helmut 2017-05-21 19:14
- lin-up/log-down any regulatory recommendation? pjs 2017-05-21 19:33
- lin-up/log-down any regulatory recommendation? Helmut 2017-05-21 19:14
- lin-up/log-down is bear’s default yjlee168 2017-05-21 20:08
- lin-up/log-down is bear’s default Yura 2017-05-25 12:52
- zero (0), missing (NA), or BLLOQ (0 or NA) in bear (II) yjlee168 2017-05-25 14:38
- zero (0), missing (NA), or BLLOQ (0 or NA) in bear (II) Yura 2017-05-25 15:17
- zero (0), missing (NA), or BLLOQ (0 or NA) in bear (II) yjlee168 2017-05-25 14:38
- lin-up/log-down is bear’s default Yura 2017-05-25 12:52
- lin-up/log-down is bear’s default Astea 2017-05-22 02:12
- Never use Excel Helmut 2017-05-22 13:19
- lin-up/log-down any regulatory recommendation? pjs 2017-05-21 19:08
- lin-up/log-down is bear’s default Helmut 2017-05-21 17:32