AUC calculation in bear [🇷 for BE/BA]

posted by pjs – India, 2017-05-21 17:57 (2503 d 09:00 ago) – Posting: # 17379
Views: 8,295

Hi all,

I have just started using bear. Thanks to the developers for this wonderful freeware.

Following is the AUC calculation done in bear for one subject data.

 subj  time    conc AUC(0-t) AUMC(0-t)
    1  0.00   0.000    0.000     0.000
    1  1.00   0.000    0.000     0.000
    1  1.50   0.000    0.000     0.000
    1  2.00   0.000    0.000     0.000
    1  2.50   0.000    0.000     0.000
    1  3.00   0.000    0.000     0.000
    1  3.50   0.000    0.000     0.000
    1  4.00   1.518    0.380     1.518
    1  4.33   5.027    1.459     6.111
    1  4.67  12.700    4.473    19.894
    1  5.00  22.210   10.233    48.004
    1  5.33  18.013   16.846    82.120
    1  5.67  22.332   23.704   119.967
    1  6.00  30.500   32.422   171.055
    1  6.33  24.290   41.423   226.493
    1  6.67  31.676   50.937   288.549
    1  7.00  32.647   61.551   361.117
    1  7.50  45.512   81.091   503.584
    1  8.00  95.827  116.425   780.573
    1 10.00 120.261  332.513  2749.799
    1 12.00  89.598  540.870  5031.520
    1 16.00  41.572  791.036  8470.430
    1 24.00  24.576 1049.699 13553.463
    1 36.00   9.237 1237.802 19015.333
    1 48.00   4.897 1319.870 22410.463
    1 72.00   1.976 1397.115 26906.872
    1 96.00   1.287 1435.682 30113.526


Now if i do manual calculation of AUC by trapezoid rule by formula, AUC is coming to 1478.681 instead of 1435.682 by bear.

Can anyone pls explain the reason for this difference.

Regards
Pjs

Edit: BBcoded; see also this post #6. [Helmut]

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