Inclusion of 3 consecutive non-zero conc data with Cmax as a last Con in PK [PK / PD]
I would like to request you please explain the rationale behind the following statement:
Concentration Time profile of a drug must have at least 3 consecutive non-zero concentration data and of which the Cmax must not be the last quantifiable concentration in order to be included in the pharmacokinetic and statistical analyses.
Thanks in advance
- Inclusion of 3 consecutive non-zero conc data with Cmax as a last Con in PKVSP 2017-05-07 21:53
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To call the statistician after the experiment is done
may be no more than asking him to perform a postmortem examination:
he may be able to say what the experiment died of.
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