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Difficulties with run NCA in BEAR [R for BE/BA]

posted by Artem Gusev - Russia, Moscow, 2017-05-02 09:56  - Posting: # 17289
Views: 3,347

Dear, yjlee168!

You are totaly right. The RDS was:

> readRDS("bearGUI.setup.rds")
                  Methods                Setting
1               run demo?                      0
2            study design                      0
3   single-/multiple-dose                      0
4       lambda_z estimate                      0
5         trapezoidal AUC                      1
6       BE criterion (LL)                     80
7                     ODA                      0
8            dose (in mg)                   <NA>
9         dosing interval                     24
10                  Tlast                    120
11                   pAUC                      0
12             pAUC_start                    121
13               pAUC_end                    128
14         indivDP_output                      0
15 drug plasma conc. unit                      1
16       is a metabolite?                      0
17           x-axis label Time after dosing (hr)
18           y-axis label     drugX plasma conc.
19         analysis types                      0
20       data file format                      0
21              Tmax_stat                      0



Manual correcting of RDS solved the problem. Thanks alot for your code.

Also at your request: Intel Core i-5 2430M, 8GB RAM, Windows 7 x64, HDD and SSD.

Best Regards,
Artem

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