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TRT / RTR Design [RSABE / ABEL]

posted by Yura - Belarus, 2017-05-01 07:34  - Posting: # 17285
Views: 1,761

Dear All
Do I understand correctly that using the TRT / RTR design it will be necessary to compare the RR and TT extension interval that are built on the data of subjects of different groups (50% of study subjects are used for RR and 50% of other subjects for TT), the comparison will be for different Subjects? Or will it be necessary to compare the extension interval R-R, built on 50% of the subjects, and the confidence interval T-R, built on the data of all subjects?
The appropriate sample size must be.
Alpha correction.
Best regards

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