Bioequivalence and Bioavailability Forum 23:10 CEST

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

TRT / RTR Design [RSABE / ABEL]

posted by Yura - Belarus, 2017-05-01 09:34  - Posting: # 17285
Views: 4,243

Dear All
Do I understand correctly that using the TRT / RTR design it will be necessary to compare the RR and TT extension interval that are built on the data of subjects of different groups (50% of study subjects are used for RR and 50% of other subjects for TT), the comparison will be for different Subjects? Or will it be necessary to compare the extension interval R-R, built on 50% of the subjects, and the confidence interval T-R, built on the data of all subjects?
The appropriate sample size must be.
Alpha correction.
Best regards

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
18,761 posts in 3,996 threads, 1,257 registered users;
online 15 (0 registered, 15 guests [including 6 identified bots]).

A drug is that substance which, when injected into a rat,
will produce a scientific report.    Anonymous

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed