Bioequivalence and Bioavailability Forum

Interesting! [General Sta­tis­tics]

posted by GM – India, 2017-03-29 22:06 (2582 d 17:53 ago) – Posting: # 17209
Views: 8,643

Dear David,

❝ For the statistical evaluation of "difference in means", to be compared with the same statistical conclusion of "difference in means" with the 90% confidence interval, the p value must be assessed against the 10% significance level. So, if your 90% Confidence Interval does not contain 1, then the p-value for formulation is also significant at the 10% significance level and may or not be also significant at the 5% significance level.

As Helmut also told in the above discussion, generally we are assessing the treatment effect @5% significance level only.

But based on your statement, it is 10% level of significance. Now I am in confusion ... whether 5% level or 10% level of significance we need to consider for BE...? Please clarify.

Thanks.
Regards,
GM

Complete thread:

• Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-27 19:40 
  • 1–2α CI and TOST at α 0.05 Helmut 2017-03-27 23:47
    • 1–2α CI and TOST at α 0.05 GM 2017-03-28 06:50
      • 1–2α CI and TOST at α 0.05 DavidManteigas 2017-03-28 11:48
        • 1–2α CI and TOST at α 0.05 ElMaestro 2017-03-28 13:12
          • alpha TOST is not alpha 2-sided d_labes 2017-03-28 15:12
            • Interesting! ElMaestro 2017-03-28 21:10
              • Google has the answer d_labes 2017-03-29 08:20
              • Interesting! DavidManteigas 2017-03-29 11:16
                • Interesting! ElMaestro 2017-03-29 11:20
                  • Interesting! DavidManteigas 2017-03-29 12:28
                    • 95% CI for a test on difference d_labes 2017-03-29 14:24
                    • Interesting!GM 2017-03-29 20:06
                      • Interesting! nobody 2017-03-30 08:24
        • Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-29 12:11
          • Relationship between calculated 90% CI and sign. treatment effect in BE DavidManteigas 2017-03-29 12:30