1–2α CI and TOST at α 0.05 [General Statistics]
❝ ❝ If the 90%CI is one side of hundred, i.e. either (85.00-98.00) or (102.00-119.00) then there should be significant treatment effect. Is this statement correct...?
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❝ Absolutely.
Hi Helmut,
Thank you for the reply.
I was also found that most of the cases above statement is correct only. But I have a situation where treatment effect is not significant even the calculated 90%CI falls one side of hundred. Is it possible..?
Actually I was used Proc GLM in SAS for this 2×2 crossover study with the model statement mentioned below:
model logCmax = Sequence Period Form Cohort Form*Cohort Subject(Sequence*Cohort)/ SS3;
Cohort was mentioned as a fixed effect because the study conducts in two groups.
The fixed effects mentioned in above the model will effect the treatment effect...? Please explain.
Regards,
GM.
—
Best Regards,
GM
Best Regards,
GM
Complete thread:
- Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-27 19:40
- 1–2α CI and TOST at α 0.05 Helmut 2017-03-27 23:47
- 1–2α CI and TOST at α 0.05GM 2017-03-28 06:50
- 1–2α CI and TOST at α 0.05 DavidManteigas 2017-03-28 11:48
- 1–2α CI and TOST at α 0.05 ElMaestro 2017-03-28 13:12
- alpha TOST is not alpha 2-sided d_labes 2017-03-28 15:12
- Interesting! ElMaestro 2017-03-28 21:10
- Google has the answer d_labes 2017-03-29 08:20
- Interesting! DavidManteigas 2017-03-29 11:16
- Interesting! ElMaestro 2017-03-29 11:20
- Interesting! DavidManteigas 2017-03-29 12:28
- 95% CI for a test on difference d_labes 2017-03-29 14:24
- Interesting! GM 2017-03-29 20:06
- Interesting! nobody 2017-03-30 08:24
- Interesting! DavidManteigas 2017-03-29 12:28
- Interesting! ElMaestro 2017-03-29 11:20
- Interesting! ElMaestro 2017-03-28 21:10
- alpha TOST is not alpha 2-sided d_labes 2017-03-28 15:12
- Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-29 12:11
- Relationship between calculated 90% CI and sign. treatment effect in BE DavidManteigas 2017-03-29 12:30
- 1–2α CI and TOST at α 0.05 ElMaestro 2017-03-28 13:12
- 1–2α CI and TOST at α 0.05 DavidManteigas 2017-03-28 11:48
- 1–2α CI and TOST at α 0.05GM 2017-03-28 06:50
- 1–2α CI and TOST at α 0.05 Helmut 2017-03-27 23:47