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Back to the forum  Query: 2017-07-27 10:32 CEST (UTC+2h)

Recipe for ABEL and adjusted α [RSABE / ABEL]

posted by Helmut Homepage - Vienna, Austria, 2017-03-23 19:10  - Posting: # 17181
Views: 950

Dear all,

since we published our paper1 about the Type I Error, I received questions about its application, regulatory acceptability, etc. In the following I summarize my answers.Answers to questions not asked:@Detlew: Something wrong or did I forget anything?

  1. Labes D, Schütz H. Inflation of Type I Error in the Evaluation of Scaled Average Bioequivalence, and a Method for its Control. Pharm Res. 2016;33(11):2805–14. doi:10.1007/s11095-016-2006-1. full-text view-only.
  2. Zheng C, Wang J, Zhao L. Testing bioequivalence for multiple formulations with power and sample size calculations. Pharm Stat. 2012;11(4):334–41. doi:10.1002/pst.1522

[image]All the best,
Helmut Schütz 

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