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Bayesian BE Assessment [Study As­sess­ment]

posted by DavidManteigas - Portugal, 2017-03-14 11:45  - Posting: # 17153
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Hi Ben,

If current frequentist methods for studies where bayesian analysis may fit (two-stage) are full of controversies in the regulators point of view, I can't even imagine if you introduce bayesian methods to them in those cases :-D

I'm not a frequentist phanatic. I believe both approaches are valid depending on the problems and study designs under consideration. Regarding bioequivalence however, I don't see how bayesian inference may add any value. The same is not true for therapeutic equivalence studies (biosimilars), where I believe bayesian methods would be very advantageous since you already "have" prior "information" regarding treatments.

Regards,
David

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