Bioequivalence and Bioavailability Forum

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log-in |  Register |  Search

Back to the forum  Query: 2017-08-17 09:47 CEST (UTC+2h)
 

Bayesian BE Assessment [Study As­sess­ment]

posted by DavidManteigas - Portugal, 2017-03-14 11:45  - Posting: # 17153
Views: 403

Hi Ben,

If current frequentist methods for studies where bayesian analysis may fit (two-stage) are full of controversies in the regulators point of view, I can't even imagine if you introduce bayesian methods to them in those cases :-D

I'm not a frequentist phanatic. I believe both approaches are valid depending on the problems and study designs under consideration. Regarding bioequivalence however, I don't see how bayesian inference may add any value. The same is not true for therapeutic equivalence studies (biosimilars), where I believe bayesian methods would be very advantageous since you already "have" prior "information" regarding treatments.

Regards,
David

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum | Admin contact
17,199 Posts in 3,683 Threads, 1,054 registered users;
32 users online (0 registered, 32 guests).

To call the statistician after the experiment is done
may be no more than asking him to perform a postmortem examination:
he may be able to say what the experiment died of.    R.A. Fisher

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
XHTML/CSS RSS Feed