Bioequivalence and Bioavailability Forum

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

Back to the forum  2018-07-20 18:53 CEST (UTC+2h)

Not estimable in the model [BE/BA News]

posted by ElMaestro - Denmark, 2017-03-14 11:02  - Posting: # 17152
Views: 6,669

Hi The user,

» I decided to continue the topic (moreover Simon kindly directed me here).
» Regarding "Not estimable". Could you please share your expirience with following issue? When I use such a model: Sequence+Period+Treatment+Group+Patient(Sequence) I get "Not estimable" in the results of ABE in WNL. Model is wrong? When I delete the "group" than error dissapeares. Comments: it is BE cross over study in 3 groups and all effects are fixed.

Hmmmm... thinking loud here... In a type III model Group will have in your case up to three columns in the model matrix, but every column is equally represented by the subjects in the respective groups. Hence Group has zero df's and no effect for any level of Group can be estimated.

Try a type I model with Group before Subjects, then you'll get something that is estimable, I believe.

if (3) 4

Best regards,
ElMaestro

"(...) targeted cancer therapies will benefit fewer than 2 percent of the cancer patients they’re aimed at. That reality is often lost on consumers, who are being fed a steady diet of winning anecdotes about miracle cures." New York Times (ed.), June 9, 2018.

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
18,547 posts in 3,941 threads, 1,190 registered users;
online 13 (1 registered, 12 guests [including 11 identified bots]).

If there is an exception to any rule,
and if it can be proved by observation,
that rule is wrong.    Richard Feynman

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed