Bioequivalence and Bioavailability Forum

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

Back to the forum  2018-06-22 19:40 CEST (UTC+2h)

Not estimable in the model [BE/BA News]

posted by ElMaestro - Denmark, 2017-03-14 11:02  - Posting: # 17152
Views: 6,378

Hi The user,

» I decided to continue the topic (moreover Simon kindly directed me here).
» Regarding "Not estimable". Could you please share your expirience with following issue? When I use such a model: Sequence+Period+Treatment+Group+Patient(Sequence) I get "Not estimable" in the results of ABE in WNL. Model is wrong? When I delete the "group" than error dissapeares. Comments: it is BE cross over study in 3 groups and all effects are fixed.

Hmmmm... thinking loud here... In a type III model Group will have in your case up to three columns in the model matrix, but every column is equally represented by the subjects in the respective groups. Hence Group has zero df's and no effect for any level of Group can be estimated.

Try a type I model with Group before Subjects, then you'll get something that is estimable, I believe.

if (3) 4

Best regards,

"(...) targeted cancer therapies will benefit fewer than 2 percent of the cancer patients they’re aimed at. That reality is often lost on consumers, who are being fed a steady diet of winning anecdotes about miracle cures." New York Times (ed.), June 9, 2018.

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
18,418 posts in 3,912 threads, 1,173 registered users;
online 43 (1 registered, 42 guests [including 30 identified bots]).

The greatest shortcoming of the human race is our inability
to understand the exponential function.    Albert Bartlett

BEBAC Ing. Helmut Schütz