“Punkteinwaage” [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2017-02-23 16:41 (2590 d 02:49 ago) – Posting: # 17100
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Hi Relaxation,

❝ I am also not aware of any guideline giving a requirement that there should be different concentrations.


There is none.

❝ is there really any rule, that CC and QC concentrations have to differ at all? And why would it be common sense, that they should be different, as long as I do not use the same stock solution?

❝ I just can't see a reason (but I am also by no means a bioanalyst).


I was an analytical chemist. ;-)
If you use different stock solutions you would get identical concentrations only if the analyst managed to achieve a <lang="de"> Punkteinwaage </lang="de"> (sorry, don’t know the English term), i.e., weigh-in identical – desired – amounts. Since this is very difficult, it is common sense that concentrations of calibrators and QCs generally differ (slightly).

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