Bioequivalence and Bioavailability Forum

Which GMR to plug in [Two-Stage / GS Designs]

posted by BE-proff – 2017-02-21 12:35 (2619 d 14:12 ago) – Posting: # 17094
Views: 12,903

Hi ElMaestro,

I suppose you are talking about futility studies as a alternative for adaptive designs.

Why are futility designs more popular if risks are similar?

Complete thread:

• Data for 2nd stage of Potvin’s designs BE-proff 2017-02-18 06:40 
  • Data for 2nd stage of Potvin’s designs ElMaestro 2017-02-18 10:20
    • Data for 2nd stage of Potvin’s designs BE-proff 2017-02-18 13:29
      • GMR = fixed! Helmut 2017-02-18 16:23
  • “Type 1” slightly higher power than “Type 2” for the same adj. α Helmut 2017-02-18 11:51
    • “Type 1” slightly higher power than “Type 2” for the same adj. α BE-proff 2017-02-18 13:31
      • Terminology Helmut 2017-02-18 16:27
        • Terminology Yura 2017-02-20 11:28
          • Which GMR to plug in ElMaestro 2017-02-20 11:46
            • Which GMR to plug inBE-proff 2017-02-21 11:35
              • Which GMR to plug in ElMaestro 2017-02-21 11:47
          • Validated frameworks; observed GMR not relevant Helmut 2017-02-22 12:03
            • Validated frameworks; observed GMR not relevant Silva 2017-03-09 01:26
              • GMR, theta 0 and that all d_labes 2017-03-09 09:21
                • GMR, theta 0 and that all Silva 2017-03-09 12:38
                  • GMR, theta 0 and that all ElMaestro 2017-03-09 12:56
                  • GMR, theta0 and that all d_labes 2017-03-09 13:55
                    • GMR, theta0 and that all Silva 2017-03-09 18:01
    • “Type 1” slightly higher power than “Type 2” for the same adj. α BE-proff 2017-02-21 11:31