Data for 2nd stage of Potvin’s designs [Two-Stage / GS Designs]
Hi All,
I have some questions on Potvin's designs:
1) is it correct that GMR and CV are required for sample size calculation for 2nd stage in all Potvin's designs?
2) Why Method C is considered "better" for sponsors than Method B?
The 1st question arised because Potvin's article dated 2007 says that only CV is needed for A and B while Method C uses both GMR and CV.
But on the other hand there are also opinions that all methods require GMR and CV.
Unclear....
I have some questions on Potvin's designs:

1) is it correct that GMR and CV are required for sample size calculation for 2nd stage in all Potvin's designs?
2) Why Method C is considered "better" for sponsors than Method B?
The 1st question arised because Potvin's article dated 2007 says that only CV is needed for A and B while Method C uses both GMR and CV.
But on the other hand there are also opinions that all methods require GMR and CV.
Unclear....

Complete thread:
- Data for 2nd stage of Potvin’s designs - BE-proff, 2017-02-18 06:40 [Two-Stage / GS Designs]
- Data for 2nd stage of Potvin’s designs - ElMaestro, 2017-02-18 10:20
- Data for 2nd stage of Potvin’s designs - BE-proff, 2017-02-18 13:29
- GMR = fixed! - Helmut, 2017-02-18 16:23
- Data for 2nd stage of Potvin’s designs - BE-proff, 2017-02-18 13:29
- “Type 1” slightly higher power than “Type 2” for the same adj. α - Helmut, 2017-02-18 11:51
- “Type 1” slightly higher power than “Type 2” for the same adj. α - BE-proff, 2017-02-18 13:31
- Terminology - Helmut, 2017-02-18 16:27
- Terminology - Yura, 2017-02-20 11:28
- Which GMR to plug in - ElMaestro, 2017-02-20 11:46
- Which GMR to plug in - BE-proff, 2017-02-21 11:35
- Which GMR to plug in - ElMaestro, 2017-02-21 11:47
- Which GMR to plug in - BE-proff, 2017-02-21 11:35
- Validated frameworks; observed GMR not relevant - Helmut, 2017-02-22 12:03
- Validated frameworks; observed GMR not relevant - Silva, 2017-03-09 01:26
- GMR, theta 0 and that all - d_labes, 2017-03-09 09:21
- GMR, theta 0 and that all - Silva, 2017-03-09 12:38
- GMR, theta 0 and that all - ElMaestro, 2017-03-09 12:56
- GMR, theta0 and that all - d_labes, 2017-03-09 13:55
- GMR, theta0 and that all - Silva, 2017-03-09 18:01
- GMR, theta 0 and that all - Silva, 2017-03-09 12:38
- GMR, theta 0 and that all - d_labes, 2017-03-09 09:21
- Validated frameworks; observed GMR not relevant - Silva, 2017-03-09 01:26
- Which GMR to plug in - ElMaestro, 2017-02-20 11:46
- Terminology - Yura, 2017-02-20 11:28
- Terminology - Helmut, 2017-02-18 16:27
- “Type 1” slightly higher power than “Type 2” for the same adj. α - BE-proff, 2017-02-21 11:31
- “Type 1” slightly higher power than “Type 2” for the same adj. α - BE-proff, 2017-02-18 13:31
- Data for 2nd stage of Potvin’s designs - ElMaestro, 2017-02-18 10:20