AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone [PK / PD]

posted by anky1212 – India, 2016-12-27 16:43 (2648 d 17:48 ago) – Posting: # 16886
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❝ I can see two options:

  1. if you are sure that healthy volunteers are ethically acceptable you could randomize more people to cover possible dropouts due to vomiting

  2. to utilize patients

Thanks for reply.

We are planning to enroll healthy human volunteer. My only concern is to use appropriate antiemetic drug which was used previously in trial/ BE study of LCE.

Please suggest appropriately.

Thanks

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